William J Jagust Selected Research

florbetapir

10/2021	Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach.
1/2021	Temporal Dynamics of β-Amyloid Accumulation in Aging and Alzheimer Disease.
10/2020	Association of CSF Aβ, amyloid PET, and cognition in cognitively unimpaired elderly adults.
1/2020	Detecting earlier stages of amyloid deposition using PET in cognitively normal elderly adults.
1/2018	Memory decline accompanies subthreshold amyloid accumulation.
1/2017	Alzheimer Disease Signature Neurodegeneration and APOE Genotype in Mild Cognitive Impairment With Suspected Non-Alzheimer Disease Pathophysiology.
4/2016	Amyloid negativity in patients with clinically diagnosed Alzheimer disease and MCI.
1/2016	Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology.
12/2015	Regional brain hypometabolism is unrelated to regional amyloid plaque burden.
10/2015	Comparison of Visual and Quantitative Florbetapir F 18 Positron Emission Tomography Analysis in Predicting Mild Cognitive Impairment Outcomes.

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William J Jagust Research Topics

Disease

139	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 09/2003
67	Cognitive Dysfunction 01/2022 - 09/2003
35	Dementia (Dementias) 01/2022 - 08/2002
33	Atrophy 01/2022 - 10/2003
6	Disease Progression 01/2022 - 02/2015
6	Vascular Diseases (Vascular Disease) 10/2021 - 09/2003
6	Amyloidosis 01/2020 - 10/2008
6	Cerebrovascular Disorders (Cerebrovascular Occlusion) 12/2013 - 10/2003
5	Frontotemporal Dementia (Semantic Dementia) 01/2018 - 05/2015
4	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2018 - 02/2011
3	Tauopathies 01/2022 - 02/2013
3	Infarction (Infarctions) 03/2015 - 10/2003
2	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2004
2	Prodromal Symptoms 01/2021 - 01/2013
2	Parkinson Disease (Parkinson's Disease) 01/2018 - 10/2017
2	Primary Progressive Aphasia 01/2018 - 10/2008
2	Neurobehavioral Manifestations 01/2018 - 01/2010
2	Corticobasal Degeneration 10/2017 - 01/2016
2	Amyloid Plaque 12/2015 - 12/2012
2	Cerebrovascular Trauma 03/2015 - 04/2013
2	Stroke (Strokes) 11/2012 - 02/2003
2	Hypertension (High Blood Pressure) 05/2006 - 10/2003
2	Hyperhomocysteinemia 12/2005 - 09/2003
1	Diaschisis 01/2021
1	Memory Disorders (Memory Loss) 10/2019
1	Anxiety Disorders (Anxiety Disorder) 01/2019
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2019
1	Craniocerebral Trauma (Head Injury) 01/2019
1	Schizophrenia (Dementia Praecox) 01/2018
1	Cerebral Small Vessel Diseases 01/2018
1	Pick Disease of the Brain (Pick's Disease) 01/2018
1	Ischemia 01/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018
1	Aphasia (Dysphasia) 01/2018
1	Brain Diseases (Brain Disorder) 01/2018
1	Gambling (Pathological Gambling) 01/2018
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 10/2017
1	Sleep Deprivation 01/2016
1	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 05/2015
1	Pica (Geophagia) 01/2014
1	Siderosis 10/2013
1	Substance-Related Disorders (Drug Abuse) 10/2013
1	Proteostasis Deficiencies 02/2013
1	Amyloid angiopathy 01/2013
1	Myocardial Infarction 11/2012
1	Brain Infarction 11/2012
1	Alcoholism (Alcohol Abuse) 01/2012
1	Hyperphagia (Overeating) 01/2010
1	Weight Loss (Weight Reduction) 01/2010
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 12/2006

Drug/Important Bio-Agent (IBA)

110	Amyloid (Amyloid Fibrils)IBA 10/2022 - 10/2008
54	Biomarkers (Surrogate Marker)IBA 10/2022 - 05/2009
25	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 08/2002
23	Apolipoproteins E (ApoE)IBA 01/2022 - 02/2003
18	ApolipoproteinsIBA 01/2022 - 02/2003
18	florbetapirIBA 10/2021 - 10/2012
17	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2021 - 10/2008
11	Amyloid beta-PeptidesIBA 01/2022 - 01/2010
10	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 04/2022 - 02/2017
7	Apolipoprotein E4IBA 01/2021 - 12/2006
6	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 01/2010
6	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2021 - 02/2011
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2015
3	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 01/2022 - 01/2018
3	Biological ProductsIBA 01/2021 - 05/2011
3	tau Proteins (tau Protein)IBA 10/2019 - 11/2013
3	Peptides (Polypeptides)IBA 01/2017 - 01/2010
3	HomocysteineIBA 02/2007 - 09/2003
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2022 - 01/2019
2	CarbonIBA 01/2018 - 02/2012
2	Blood Proteins (Serum Proteins)IBA 10/2015 - 02/2015
2	Folic Acid (Vitamin M)FDA LinkGeneric 02/2007 - 12/2005
2	Vitamin B Complex (B Vitamins)IBA 02/2007 - 09/2003
1	antineoplaston A10 (A 10)IBA 01/2022
1	Hormones (Hormone)IBA 01/2022
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2022
1	FluorineIBA 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2020
1	LigandsIBA 01/2020
1	A-factor (Streptomyces)IBA 01/2019
1	TESIBA 01/2019
1	THK5351IBA 01/2018
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 02/2017
1	Docosahexaenoic AcidsIBA 10/2016
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2016
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2016
1	HemosiderinIBA 10/2013
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 10/2013
1	Cholinergic Agents (Cholinergics)IBA 01/2013
1	Cholinesterases (Cholinesterase)IBA 01/2013
1	Narcotic Antagonists (Opioid Antagonists)IBA 01/2012
1	Naltrexone (ReVia)FDA LinkGeneric 01/2012
1	3-tyrosineIBA 01/2010
1	C-Reactive ProteinIBA 12/2008
1	AD 11IBA 03/2007
1	VitaminsIBA 02/2007

Therapy/Procedure

4	Therapeutics 01/2022 - 01/2014
1	Drug Therapy (Chemotherapy) 01/2022
1	Cognitive Training 07/2009